Links und Funktionen





Mörk-Mörkenstein, M.; Heermann, R.; Göpel, Y.; Jung, K.; Görke, B. (2017). Non-canonical activation of histidine kinase KdpD by phosphotransferase protein PtsN through interaction with the transmitter domain. Mol. Microbiol. doi: 10.1111/mmi.13751.

Langer, A.; Moldovan, A.; Harmath, C.; Joyce, S.; Clarke, D.; Heermann, R. (2017). HexA is a versatile regulator involved in the control of phenotypic heterogeneity of Photorhabdus luminescens, PLOS ONE 12(4):e0176535.

Schlundt, A.; Buchner, S.; Janowski, R.; Heydenreich, T.; Heermann, R.; Lassak, J.; Geerlof, A.; Stehle, R.; Niessing, D.; Jung, K.; Sattler, M. (2017). Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator. Sci. Rep. 7(1):1051.

Hellinckx, J.; Heermann, R.; Felsl, A.; Fuchs, T. (2017). High binding a nity of repressor IolR avoids costs of untimely induction of myo-inositol utilization by Salmonella Typhimurium. Sci. Rep. 7:44362.

Brameyer, S.; Heermann, R. (2017). Quorum sensing and LuxR solos in Photorhabdus. Curr Top Microbiol Immunol. 402:103-119.

Wang, Y.; Heermann, R.; Jung, K. (2017). CipA and CipB as scaffolds to organize proteins into crystalline inclusions. ACS Synth. Biol., doi: 10.1021/acssynbio.6b00323.

da Silva, J.L.; Undurraga Schwalm, F.; Eugênio Silva, C.; da Costa, M.; Heermann, R.; Santos da Silva, O (2017). Larvicidal and growth-inhibitory activity of entomopathogenic bacteria culture fluids against Aedes aegypti (Diptera: Culicidae). J. Econ. Entomol. pii: tow224.

Parvin, N.,; Carrie, C.; Pabst, I.; Läßer, A.; Laha, D.; Paul, M.; Geigenberger, P.; Heermann, R.; Jung, K.; Vothknecht, U.C.; Chigri, F. (2017). TOM9.2 Is a calmodulin binding protein critical for TOM complex assembly but not for mitochondrial protein import in Arabidopsis thaliana. Mol. Plant. pii: S1674-2052(16)30336-7.

Fang, C.; Nagy-Staroń, A.; Grafe, M.; Heermann, R.; Jung, K.; Gebhard, S.; Mascher, T. (2016). Insulation and wiring specificity of BceR-like response regulators and their target promoters in Bacillus subtilis. Mol. Microbiol. doi: 10.1111/mmi.13597.

Heinrich, A.K.; Glaeser, A.; Tobias, N.J.; Heermann, R.; Bode, H.B. (2016). Heterogeneous regulation of bacterial natural product biosynthesis via a novel transcription factor. Heliyon 2(11): e00197. Free on Elsevier.

Nolle, N.; Felsl, A.; Heermann, R.; Fuchs, T.M. (2016). Genetic characterization of the galactitol utilization pathway of Salmonella enterica serovar Typhimurium. J Bacteriol. pii: JB.00595-16.

Stark, K.; Philippi, V.; Stockhausen, S.; Busse, J.; Antonelli, A.; Miller, M.; Schubert ,I.; Hoseinpour, P.; Chandraratne, S.; von Brühl, M.L.; Gärtner, F.; Lorenz, M.; Agresti, A.; Coletti, R.; Antoine, D.J.; Heermann, R.; Jung, K.; Reese, S.; Laitinen, I.; Schwaiger, M.; Walch, A.; Sperandio, M.; Nawroth, P.P.; Reinhardt, C.; Jäckel S.; Bianchi, M.E.; Massberg, S. (2016). Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood. pii: blood-2016-04-710632.

Schramke, H.; Tostevin, F.; Heermann, R.; Gerland, U.; Jung, K. (2016). A dual-sensing receptor confers robust cellular homeostasis. Cell Rep. pii: S2211-1247(16)30694-5. doi: 10.1016/j.celrep.2016.05.081.

Behr, S.; Heermann, R.; Jung, K. (2016). Insights into the DNA-binding mechanism of a LytTR-type transcription regulator. Biosci Rep. pii: BSR20160069.

Hörnschmeyer, P.; Liss, V.; Heermann, R.; Jung, K.; Hunke, S. (2016). Interaction Analysis of a Two-Component System Using Nanodiscs. PLoS One 11(2):e0149187.

Glaeser, A.; Heermann, R. (2015). A novel tool for stable genomic reporter gene integration to analyze heterogeneity in Photorhabdus luminescens at the single-cell level. Biotechniques 1;59(2):74-81.

Brameyer, S.; Bode, H.B.; Heermann, R. (2015). Languages and dialects: bacterial communication beyond homoserine lactones. Trends Microbiol. 23(9):521-523.

Brameyer, S.; Heermann, R. (2015). Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors. PLoS One 10(4):e0124093.

Brameyer, S.; Kresovic, D.; Bode, H.B.; Heermann, R. (2015). Dialkyresorcinols as bacterial signaling molecules. PNAS 112(2):572-7.

Brameyer, S.; Kresovic, D.; Bode, H.B.; Heermann, R. (2014). LuxR solos in Photorhabdus species. Front. Cell. Infect. Microbiol. 4:166. doi: 10.3389/fcimb.2014.00166. Free in Frontiers.

Dintner, S.; Heermann, R.; Fang, C.; Jung, K.; Gebhard, S. (2014). A sensory complex consisting of an ATP-binding-cassette transporter and a two-component regulatory system controls bacitracin resistance in Bacillus subtilis. J. Biol. Chem. 289(40):27899-910.

Heermann, R.; Zigann, K.; Gayer, S.; Rodriguez-Fernandez, M.; Banga, J.R.; Kremling, A.; Jung K. (2014). Dynamics of an interactive network composed of a bacterial two-component system, a transporter and K+ as mediator. PLoS One 9(2):e89671.

Fritz, G., Megerle, J.A.; Westermayer, S.A.; Brick D.; Heermann, R., Jung, K., Rädler, J.O., Gerland, U. (2014). Single Cell Kinetics of Phenotypic Switching in the Arabinose Utilization System of E. coli. PLoS One 9(2):e89532.

Schweiger, R.; Soll, J.; Jung, K.; Heermann, R.; Schwenkert, S. (2013). Quantification of interaction strengths between chaperones and tetratricopeptide repeat domain containing membrane proteins. J. Biol. Chem. 288(42):30614-25.

Brachmann, A.O.; Brameyer, S.; Kresovic, D.; Hitkova, I.; Kopp, Y.; Manske, C., Schubert, K.; Bode, H.B.; Heermann, R. (2013). Pyrones as bacterial signaling molecules, Nature Chem. Biol., 9(9):573-578.

da Silva, O.S.; Prado, G.R.; da Silva, J.L.; Silva, C.E.; da Costa, M.; Heermann, R. (2013). Oral toxicity of Photorhabdus luminescens and Xenorhabdus nematophila (Enterobacteriaceae) against Aedes aegypti (Diptera: Culicidae). Parasitol. Res., 112(8):2891-2896.

Jung, K.; Fried, L.; Behr, S.; Heermann, R. (2012). Histidine kinases and response regulators in networks, Curr. Opin. Microbiol. 15(2):118-124.

Heermann, R. & Jung, K. (2010). The complexity of the “simple” two-component system KdpD/KdpE in Escherichia coli, FEMS Microbiol. Lett., 304, 97-106.

Lüttmann, D.; Heermann, R.; Zimmer, B.; Hillmann, A.; Rampp, I.-S.; Jung, K.; Görke, B. (2009). Stimulation of the potassium sensor KdpD kinase activity by interaction with the phosphotransferase protein IIANtr in Escherichia coli, Mol. Microbiol., 72(4):978-994.

Heermann, R.; Weber, A.; Mayer, B.; Ott, M.; Hauser, E.; Gabriel, G.; Pirch, T.; Jung, K. (2009). The universal stress protein UspC scaffolds the KdpD/KdpE signaling cascade of Escherichia coli under salt stress, J. Mol. Biol., 386(1):134-148.

Heermann, R.; Lippert, M.-L.; Jung, K. (2009). Domain swapping reveals that the N-terminal domain of the sensor kinase KdpD in Escherichia coli is important for signaling, BMC Microbiol., 9:133. Free in Biomedcentral

Münch, A., Stingl, L., Jung, K., and Heermann, R. (2008). Photorhabdus luminescens genes induced upon insect infection, BMC Genomics, 9:229, status: highly accessed. Free in Biomedcentral

Heermann, R., Zeppenfeld, T., Jung, K. (2008). Simple generation of site-directed point mutations in the Escherichia coli chromosome using Red®/ET® Recombination, Microb. Cell Fact., 7:14. Free in Biomedcentral

Heermann, R. & Fuchs, T.M. (2008). Comparative analysis of the Photorhabdus luminescens and Yersinia enterocolitica genomes: uncovering candidate genes involved in insect pathogenicity, BMC Genomics, 9:40, status: highly accessed. Free in Biomedcentral

Fleischer, R.; Heermann, R.; Jung, K.; Hunke, S. (2007). Purification, reconstitution and characterization of the CpxRAP envelope stress system of Escherichia coli, J. Biol. Chem., 282(12):8583-93.

Kremling, A.; Heermann, R.; Centler, F.; Jung, K.; Gilles, E.D. (2004). Analysis of two-component signal transduction by mathematical modeling using the KdpD/KdpE system of Escherichia coli, Biosystems 78(1-3):23-37.

Heermann, R. & Jung, K. (2004). Strucutal features and mechanisms of sensing high osmolarity in microorganisms, Curr. Opin. Microbiol. 7(2):168-174.

Heermann, R.; Fohrmann, A.; Altendorf, K.; Jung, K. (2003). The transmembrane domains of the sensor kinase KdpD of Escherichia coli are not essential for sensing K+ limitation, Mol. Microbiol. 47(3):839-848.

Heermann, R.; Altendorf, K.; Jung, K. (2003). The N-terminal input domain of the sensor kinase KdpD of Escherichia coli stabilizes the interaction between the cognate response regulator KdpE and the corresponding DNA-binding site, J. Biol. Chem. 278(51):51277-84.

Ballal, A.; Heermann, R.; Jung, K.; Gaßel, M.; Apte, S.K.; Altendorf, K. (2002). A chimeric “Anabaena KdpD-E. coli KdpD C-terminal domain“ (Anacoli KdpD) protein functionally interacts with Escherichia coli KdpE and activates kdp expression, Arch. Microbiol. 178(2):141-148.

Heermann, R.; Altendorf, K.; Jung, K. (2000). The hydrophilic N-terminal domain complements the membrane-anchored C-terminal domain of the sensor kinase KdpD of Escherichia coli, J. Biol. Chem. 275 (22):17080-17085.

Heermann, R.; Altendorf, K.; Jung, K. (1998). The turgor sensor KdpD of Escherichia coli is a homodimer, Biochim. Biophys. Acta 1415:114-124.

Jung, K.; Heermann, R.; Meyer, M.; Altendorf, K. (1998). Effect of cysteine replacements on the properties of the turgor sensor KdpD of Escherichia coli, Biochim.Biophys Acta 1372:311-322.


Heermann, R. (2016). Alles hört auf (m)ein Kommando! (Rubrik: Wissenschaft-Journal Club), Biospektrum, 06.16, 22. Jahrgang, 608.

Schramke, H., Wang, Y., Heermann, R., Jung, K. (2016). Stimulus perception by histidine kinases. In de Bruijn, F.J. (Editor) Stress and environmental control of gene expression in bacteria, Wiley-Blackwell Publishers.

Heermann R. (2012). Molekularer Terror: Molekül insektenpathogener Bakterien bildet aggressiven Abwehrschild (Rubrik: Wissenschaft- Journal Club), Biospektrum 06.12, 18. Jahrgang, 621.

Heermann, R. & Jung, K. (2012). K+ supply, osmotic stress, and the KdpD/KdpE Two-component system, in R. Gross and D. Beier (eds.), Two-component systems in bacteria, Chapter 10, Caister Academic Press, Norfolk, UK.

Heermann R. (2010). „Süßes Gift“ – Wie Photorhabdus luminescens seine Opfer schädigt (Rubrik: Mikroorganismen in den Schlagzeilen), Biospektrum 04.10, 16. Jahrgang, 431.

Heermann R. (2010). Der „Leuchtende Tod“ und die Regulation von Gut und Böse (Rubrik: Habilitierte stellen sich vor), Biospektrum 03.10, 16. Jahrgang, 363.

Heermann, R. & Jung, K. (2009). Stimulus perception and signaling in histidine kinases, in R. Krämer and K. Jung (eds.), Bacterial Signaling, pp. 135-161, Wiley-VCH Verlag, Weilheim.

Heermann, R. (2005). Die leuchtende Pest – Biolumineszente Bakterien terrorisieren Insektenlarven, Jahresbericht der Münchner Universitätsgesellschaft 2005.

Jung, K. & Heermann, R. (2003). Die Komplexität bakterieller Histidinkinase/Antwortregulator-Systeme, Biospektrum, Sonderausgabe 9. Jahrgang, 456-459.